Logo

Cellular Re-programming utilizing the Immune system​

We use immune cells to deliver protein directly to the cytoplasm of diseased cells to improve patient health and longevity.

Cellular Re-programming utilizing the Immune system​

We use immune cells to deliver protein directly to the cytoplasm of diseased cells to improve patient health and longevity.

It all starts inside the cell...

1

Roughly two thirds of our body’s proteins are inside cells. These include many key disease pathway targets

2

Existing therapeutic approaches are limited by tissue tropism, toxicity or payload size

3

No currently-available technology can introduce a functional protein into a cell, and very few can target a specific tissue

In nature, immune cells deliver a toxic payload to eliminate diseased cells

Immune cells are capable of deep tissue intracellular penetration and are free of toxicity and payload size concernsa

WE REDESIGN THE IMMUNE CELLS TO DELIVER PROTEIN THERAPEUTICS INSTEAD

This opens up a new universe of targets for treatment that have not previously been translated to the clinic

Edity’s technology integrates therapeutic proteins into the perforin-granzyme pathway, delivering directly to the cytosol of target cells.

Sophisticated protein design and highly efficient transformation protocols ensure superior protein expression and transferability

Constitutively active Immune Sensors​

The therapeutic protein is an immune sensor, that was engineered to constitutively activate its downstream pathway, independently of the presence of activating nucleic acids (AIS)​

Plug And Play Technology

Builds on clinical grade technologies

Compatible with
autologous / allogeneic
approaches

Shown to work with T-cells, NK cells

Edity’s technology can use CAR, TCR or similar modalities to homing and activation.

Plug And Play Technology

Builds on clinical grade technologies

Compatible with autologous / allogeneic approaches

Shown to work with T-cells, NK cells

Edity’s technology can use CAR, TCR or similar modalities to homing and activation.

Creating new modalities
for intracellular therapy

We deliver proteins to cells anywhere in the body

Creating new modalities
for intracellular therapy

We deliver proteins to cells anywhere in the body

Publications

ABOUT US

Edity is developing an exciting new platform that harnesses the immune system to deliver therapeutic proteins direct to the cytoplasm of target cells to reprogram cells and tissue back to health.

The technology creates the opportunity to change the course of disease at the intracellular level via multiple mechanisms including protein replacement, target modulation, genetic correction and protein gain of function.  Currently, the company is working across a number of indications, including oncology and genetic disease, while developing programs for regeneration and longevity.

Our People

Eyal is a serial entrepreneur and has devoted the majority of his career to building medical device companies. He founded TopSpin medical, Pi-Cardia and Clear-Cut.

Eyal Kolka​

CO-FOUNDER, CHAIRMAN OF THE BOARD​

Michal is graduate of the Weizmann Institute of Science and a seasoned expert in gene editing and genetic screening, having spent four years at Emendo before going onto found her own company, Applied Genetics. Michal founded Edity in 2020.

Michal Golan-Mashiach
PhD, MBA

CO-FOUNDER AND CEO

Ofer is an expert in tumor immunology and has gained a strong industrial experience in Compugen focusing on target validation of immuno-oncology programmes.

Ofer Levy, PhD

VP R&D

Sharon is an experienced biochemist and renowned oligo nucleotides expert. At QBI, she headed the entire planning of pre-clinical studies the pre-clinical siRNA pipeline, including in vitro and in vivo trials.

Sharon Avkin Nachum, PhD​

VP TECHNOLOGY 

Assaf is an expert in CAR-T science and has had positions at the Weizmann Institute, UC Berkely and AbbVie. He is an inventor on one of the first allogeneic CAR T cell patents.

Assaf Marcus, PhD

VP TRANSLATIONAL SCIENCE

Scientific Advisors

Reuben S. Carpentier Professor, Columbia University. An international leader in the immunobiology of human NK cells

Jordan S. Orange

Columbia University

American Cancel Society Proffessor and Chair of the department of Microbiology and Immunology, UCSF. An Inetrnationally-recognized expert in naturall (NK) cells.

Lewis Lanier

UCSF

Carsten Watzl has a long-standing research interest in investigating the regulation and the functional activities of Natural Killer (NK) cells. His work has contributed to fundamental processes in NK cell biology.

Carsten Watzl

Technical University Dortmund

Richard ‘Rick’ Kendall has more than 30 years of experience in biotechnology and the biopharmaceutical industry including executive positions at Kite pharma and Amgen. Most recently he served as CEO at ImmPACT-Bio USA Inc.

Rick Kendall

ImmPACT-Bio USA Inc.

One of the pioneers of CAR-T. Head of the Immunology Lab, MIGAL .Former Dean of the Faculty of Sciences and Technology, Tel-Hai. Founder of ImmPACT Bio, Co-founder of GentiBio.

Gideon Gross

ImmPACT Bio

Professor Yoram Reiter is a world leader in immunotherapy. His research is focused on targeting the intracellular proteome, T cell biology and CAR-T cell engineering.

Yoram Reiter

Technion

Investors

CONTACT US

+972-54-7414417
info@edity-tx.com
10 Menachem Plaut St.
7670609, Rehovot, IL